CRP Testing Essentials: Reliable,Affordable,and Clinically Relevant-poclightbio.com

1. What It Is

C-reactive protein (CRP) is an acute-phase protein mainly produced by the liver into the blood in response to inflammation. CRP levels rise rapidly following inflammatory stimuli and decline promptly once the trigger resolves, making it a valuable tool for early diagnosis and treatment monitoring.

Parameter	C-reactive protein (CRP)
Primary Site of Production	Liver
Clinical Utility	● Monitor inflammation and guide patient management ● Differentiate bacterial from viral infections: CRP level ≥ 50 mg/L are linked to bacterial infections in ~ 90% of cases
CRP Response & Half-life	● Onset of increase: 6–8 hours ● Peak: 24–48 hours ● Half-life: ~19 hours

2. Why It Matters

(1) Reliable biomarker: Clinically validated indicator of systemic inflammation, infection, autoimmune disorders, and cardiovascular risk.

(2) Actionable insights: Supports differential diagnosis (bacterial vs viral), informs antibiotic prescribing, and monitors disease activity to guide treatment.

(3) POC advantage: Rapid, on-site testing enables timely clinical decisions in primary care, emergency, and bedside settings.

3. Reference Ranges:

Item	Result	Interpretation
High-sensitivity C-reactive protein (hs-CRP Assay Kit) (assessing risk of cardiovascular events)	1 mg/L	Low cardiovascular risk
	1–3 mg/L	Moderate cardiovascular risk; anti-inflammatory therapy recommended
	≥ 3 mg/L	High cardiovascular risk; anti-inflammatory and antithrombotic therapy recommended
C-Reactive Protein (CRP Test Kit)	< 10 mg/L	Normal
	> 10 mg/L	Indicates inflammation; possible infection, autoimmune disease, or chronic inflammation
	> 50 mg/L	Indicates bacterial infection (~90%); viral infection uncommon
	> 100 mg/L	Severe elevation, generally seen in acute bacterial infections

Note: Results should be interpreted in the context of the patient’s clinical condition. Laboratories are recommended to establish population-specific reference values for their region, as the levels may vary with demographic and methodological factors.

4. When and Where to Measure CRP

Clinical Setting	When / Indication	Purpose / Clinical Use
Primary care / Outpatient clinics	At onset of acute symptoms; routine follow-up for chronic inflammation	Rapid assessment of infection; guide antibiotic use; monitor autoimmune disease activity
Emergency department / Urgent care	Suspected acute infection, fever, or trauma	Triage patients; monitor acute inflammation and treatment response
Hospital / Laboratory / ICU	Post-surgery, trauma, sepsis, or during treatment	Assess inflammation; monitor therapy effectiveness, and track disease progression

Application Scenario

5. Why Poclight CRP Stands Out: Facts & Features

Poclight CRP Test Kit

(1) Assay Specifications

Item	Specification / Value
Detection Limit (LOD)	≤ 0.5 mg/L
Measurement Range	0.5 - 320 mg/L within this linear range, the linear correlation coefficient r should be not less than 0.990
Sample Volume	5 μL
Sample Type	Serum, Plasma, Whole Blood
Assay Time / Turnaround	3 min
Precision (CV%)	5%
Reference Range	<10 mg/L

(2) Key Features:

a. Advanced patent technology: 5th generation homogenous CLIA, CRET technology

b. Compatible with Poclight C5000 analyzer: Designed for POC settings, auto-calibration, built-in scanner, internal mixing component, and more

C5000 POC CLIA C5000 Specifications

c. Individually packaged: on-demand testing

d. Room-temperature transport, no cold chain required: saves logistic costs

e. Lyophilized reagents: freeze-dried reagent for room temperature storage (2–30°C) with extended shelf life of 18 months

f. Operational efficiency: intuitive process, reduced workload, and optimal lab performance

CRP Operation

Tags : Rapid CRP Diagnostic Kit CRP Analyzer CRP Lyophilized Ball Reagent Test Kit

CRP Testing Essentials: Reliable, Affordable, and Clinically Relevant

1. What It Is

2. Why It Matters

3. Reference Ranges:

4. When and Where to Measure CRP

5. Why Poclight CRP Stands Out: Facts & Features