World Stroke Day is observed on October 29 to underscore the serious nature and high rates of stroke, raise awareness of the prevention and treatment of the condition, and ensure better care and support for survivors. Stroke and platelet function Stroke refers to an acute cerebrovascular disease caused by the sudden rupture of blood vessels in the brain or the sudden interruption of blood flo...
Major risk factors for cardiovascular disease Hypertension: one of the main controllable risk factors, accounting for 50% of cardiovascular disease morbidity and 20% of deaths, but the awareness rate is only 46.9%, and the blood pressure control rate is even lower to 15.3%. Dyslipidemia: Studies have shown that the awareness, treatment and control rates of dyslipidemia in ≥ 18-year-olds need to...
Infectious diseases are one of the common diseases in the emergency department, and the systemic inflammatory response syndrome caused by infection is the most fundamental pathophysiological change in sepsis. Due to the complexity of the systemic inflammatory response, there are no ideal diagnostic, stratification, prognostic tools, and effective treatment options. A number of studies have demonst...
Chemiluminescence immunoassay technology has long been well-known in the field of in vitro diagnostics! These include, direct chemiluminescence, electrochemiluminescence, enzymatic chemiluminescence, indirect chemiluminescence. So many types of luminescence use luminescent agents that are also very different!1. Acridine ester Direct chemiluminescence Acridine ester (AE) is a tricyclic organic...
In vitro diagnostic reagent stability refers to the ability of an in vitro diagnostic medical device to maintain its performance characteristics within the limits specified by the manufacturer, reflecting the product's ability to grow with In the process of storage, transportation and use of in vitro diagnostic reagents, various influencing factors such as temperature, humidity, light, repe...
B-type natriuretic peptide (BNP) and N-terminal B-type natriuretic peptide precursor (NT-proBNP) are biomarkers of cardiac function, as well as the preferred biomarkers for the diagnosis and differential diagnosis of heart failure, disease severity and prognosis assessment, and have been recommended as Level I by several clinical practice guidelines. BNP is mainly degraded in large blood ves...
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess ...
World Heart Day was created by the World Heart Federation to inform people around the world that cardiovascular disease (CVD), including heart disease and stroke, is the leading cause of death in the world. This year's theme is " Heart and Action Integration ", which emphasizes the close connection between heart health and our daily behavior and reminds us to maintain and promote ...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...